F-Shaped Pattern For Reading Web Content

Eyetracking visualizations show that users often read Web pages in an F-shaped pattern: two horizontal stripes followed by a vertical stripe.
F-Shaped Pattern For Reading Web Content (Useit.com)

Your goal as a web author is to put your best stuff in the hotspots. Obviously you can direct the user’s attention somewhat, using whitespace and graphics. But note how little attention readers devote to the boxed content on either side of the main column.