This is Dan Rather’s profile. Expanded to the nth degree. Taken to infinity. Overlayed on the back of Patrick Stewart’s head. It’s recombinant phrenology. The elements of phrenology recombined in ways that follow the rules of irrational logic, a rigorous methodology that follows nonrational rules. It is a structure for following your intuition and your obsessions. It is the hyperfocused scribblings of the mad and the gifted. — David Byrne
—Learning to Love PowerPoint (Wired)

Byrne uses PowerPoint as his medium. His commentary on Dolly the genetically engineered sheep is also very good.